Which is stronger protonix or prilosec

While rare, other adverse reactions like bone fractures and memory loss have also been linked to long-term use of PPIs Makunts, So far, studies have found pantoprazole to have fewer drug interactions compared to omeprazole Wedemeyer, Omeprazole and pantoprazole are safe for most people to use, with a few exceptions.

There are no adequate studies yet on either drug about the risks for women who are nursing or pregnant. While omeprazole is considered to be safe for children over the age of one year, pantoprazole can be prescribed by a healthcare provider in very specific circumstances for children five years of age and up FDA, While more research is still needed, studies have found that PPIs may be more dangerous for those living with or at risk of migraines, visual impairment, and memory problems Makunts, Since PPIs are intended for short-term use, any prolonged use of either drug could increase the risks for adverse effects or even death.

A large study found that PPI users had a greater risk of death compared to patients taking H2 blockers or no stomach acid-reducing medications at all Xie, Talk to a healthcare provider before taking either omeprazole or pantoprazole. Do not take these drugs together as it could increase the risk of side effects.

For more information about side effects and safety, you can check out the medication pamphlets for Prilosec omeprazole and Protonix pantoprazole. Last updated October 6, Written by Anna Brooks. Disclaimer If you have any medical questions or concerns, please talk to your healthcare provider.

Vitals Omeprazole and pantoprazole are popular drugs used to manage and treat conditions including chronic heartburn, gastroesophageal reflux disease GERD , and erosive esophagitis. Both drugs are types of proton pump inhibitors PPIs , a class of drugs that helps combat heartburn by suppressing acid production in the stomach. Omeprazole and pantoprazole are safe, well-tolerated, and considered to be equally effective; however, if taken incorrectly, they can cause serious side effects.

The main differences between these two medications are cost, dosage, and potential drug interactions. Learn more. Related articles. What can pantoprazole and PPIs be used for?

Does omeprazole have serious drug interactions? Omeprazole is known by its brand name, Prilosec, and can be purchased with a prescription or over-the-counter. Like pantoprazole, it works as a proton pump inhibitor to treat GERD.

However, it is also FDA-approved to treat helicobacter pylori H. Omeprazole can treat GERD in adults and children aged 1 year and older. It comes as a delayed-release capsule, tablet, and liquid suspension. PPIs like pantoprazole and omeprazole are more potent than regular antacids and histamine H2 blockers. PPIs are usually prescribed as a short-term treatment that is taken for up to 8 weeks. Pantoprazole and omeprazole can also treat hypersecretory conditions that cause the stomach to produce too much acid.

Zollinger-Ellison syndrome is a condition that involves tumors in the pancreas or duodenum part of the small intestine.

Pantoprazole and omeprazole can also help treat other conditions such as peptic ulcers, which include both duodenal ulcers and stomach ulcers.

These ulcers are often caused by an infection from a bacteria called H. While omeprazole is FDA-approved to treat H. Pantoprazole and omeprazole have been shown to be effective for treating GERD. In a meta-analysis that pooled over 40 different studies, results found no significant differences in effectiveness between these PPIs. Pantoprazole was found to be equally as effective as omeprazole.

Some double-blind clinical trials in the meta-analysis also compared other PPIs such as Nexium esomeprazole , lansoprazole Prevacid , and rabeprazole Aciphex. One study found that pantoprazole was more effective than omeprazole in the treatment of stomach ulcers.

Effectiveness was determined based on how fast the ulcers healed. Pantoprazole was found to be more effective in the study, although a high dosage may have played a role in its effectiveness. Pantoprazole and omeprazole are both comparable drugs in terms of effectiveness.

One may be preferred over the other depending on the condition being treated and the cost of the medication. Consult a doctor to determine which PPI may be better for you.

Pantoprazole is a generic medication that is usually covered by Medicare and most insurance plans. Omeprazole is a generic medication that is usually covered by Medicare and most insurance plans.

Pantoprazole and omeprazole can cause side effects such as headache, dizziness, nausea, and vomiting. They can also cause other gastrointestinal side effects, such as diarrhea, constipation, abdominal pain, and gas. Other possible side effects may include joint pain, upper respiratory tract infections, and asthenia, or lack of energy. Omeprazole can also cause side effects such as back pain and coughing. Pantoprazole has not been found to cause these particular side effects as often as omeprazole.

Source: DailyMed pantoprazole , DailyMed omeprazole. Both pantoprazole and omeprazole can interact with the same drugs. They both can interact with antiretroviral medications such as rilpivirine, atazanavir, and saquinavir. Taking these medications together can alter the effectiveness of the antiretroviral drug and increase its toxicity. Some drugs that affect blood clotting should not be taken with certain PPIs.

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Contact afpserv aafp. Want to use this article elsewhere? Get Permissions. Read the Issue. Sign Up Now. Previous: Newsletter. Next: The Safety of Caffeine Consumption. Nov 1, Issue. From left: Dr. Mark Graber, Dr. Andrea Darby-Stewart, and Dr.

Robert Dachs. Purpose Each month, three presenters will review an interesting journal article in a conversational manner. Is one PPI better than another? What does this article say? Six studies of lansoprazole Prevacid 30 mg versus omeprazole 20 mg found no difference.

Two studies of rabeprazole Aciphex 20 mg versus omeprazole 20 mg found no difference. Should we believe this study? What should the family physician do? Read the full article.

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